Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.48 |
| ▸ | HMGCR | P04035 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883539 | 0.97 | PTPN7 (0.50) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL5129440 | 0.87 | PTPN7 (0.50) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL11654013 | 0.87 | PTPN7 (0.50) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL28587196 | 0.87 | PTPN7 (0.50) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3123632 | 0.87 | PTPN7 (0.50) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL5883458 | 0.87 | — | — | |
| SCHEMBL6750440 | 0.84 | PTPN7 (0.46) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL23040316 | 0.84 | PTPN7 (0.61) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL9211891 | 0.84 | PTPN7 (0.61) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL9374800 | 0.84 | PTPN7 (0.61) | PTPN7HMGCRRECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243143-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | AGAIN BIO APS (DK) | 2025-07-31 | — | — | US | disclosed |
| US-12304883-B2 | 1,3-fatty diol compounds and derivatives thereof | GENOMATICA, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| CN-114773160-B | 1, 3-Aliphatic diol compound and derivative thereof | 基因组股份公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-4223765-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | Genomatica, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3795576-B1 | 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF | GENOMATICA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-114773160-A | 1, 3-aliphatic diol compound and derivative thereof | 基因组股份公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109890783-B | 1, 3-aliphatic diol compound and derivative thereof | 基因组股份公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220098133-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | AGAIN BIO APS (DK) | 2022-03-31 | — | — | US | disclosed |
| US-11168046-B2 | 1,3-fatty diol compounds and derivatives thereof | GENOMATICA, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| EP-3795576-A1 | 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF | Genomatica, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20200385325-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | GENOMATICA, INC. (US) | 2020-12-10 | — | — | US | disclosed |
| EP-3512825-B1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | GENOMATICA INC (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10570074-B2 | 1,3-fatty diol compounds and derivatives thereof | GENOMATICA, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180072645-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | REG LIFE SCIENCES LLC (US) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570074-B2 | 1,3-fatty diol compounds and derivatives thereof | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-20250243143-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-20180072645-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-12304883-B2 | 1,3-fatty diol compounds and derivatives thereof | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-11168046-B2 | 1,3-fatty diol compounds and derivatives thereof | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-20200385325-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
| US-20220098133-A1 | 1,3-Fatty Diol Compounds And Derivatives Thereof | DGAT1, DGAT2, DSG1 | PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.