Sugi Predict

Sugi Predict / Compounds / SCHEMBL5883539

SCHEMBL5883539

SCHEMBL5883539

CCCCCCC#CCCBr

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN7 P35236 5/20 0.50
▸ HMGCR P04035 3/20 0.50
▸ RECQL P46063 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ TSHR P16473 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX2 P34913 3/20 0.39
▸ RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19948787 0.97 PTPN7 (0.48) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL11654013 0.90 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL5129440 0.90 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL28587196 0.90 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3123632 0.90 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL5883458 0.89 — —
SCHEMBL6750440 0.86 PTPN7 (0.46) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL23040316 0.86 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL1523678 0.86 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL513302 0.86 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof AGAIN BIO APS (DK) 2025-07-31 — — US disclosed
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2025-05-20 — — US disclosed
CN-114773160-B 1, 3-Aliphatic diol compound and derivative thereof 基因组股份公司 2025-03-07 — — CN disclosed
EP-4223765-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF Genomatica, Inc. (US) 2023-08-09 — — EP disclosed
EP-3795576-B1 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF GENOMATICA INC (US) 2023-06-07 — — EP disclosed
CN-114773160-A 1, 3-aliphatic diol compound and derivative thereof 基因组股份公司 2022-07-22 — — CN disclosed
CN-109890783-B 1, 3-aliphatic diol compound and derivative thereof 基因组股份公司 2022-06-14 — — CN disclosed
US-20220098133-A1 1,3-Fatty Diol Compounds And Derivatives Thereof AGAIN BIO APS (DK) 2022-03-31 — — US disclosed
US-11168046-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2021-11-09 — — US disclosed
EP-3795576-A1 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF Genomatica, Inc. (US) 2021-03-24 — — EP disclosed
US-20200385325-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF GENOMATICA, INC. (US) 2020-12-10 — — US disclosed
EP-3512825-B1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF GENOMATICA INC (US) 2020-10-21 — — EP disclosed
US-10570074-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2020-02-25 — — US disclosed
EP-3512825-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF REG Life Sciences, LLC (US) 2019-07-24 — — EP disclosed
WO-2018053202-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF REG LIFE SCIENCES LLC (US) 2018-03-22 — — WO disclosed
US-20180072645-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF REG LIFE SCIENCES LLC (US) 2018-03-15 — — US disclosed
US-7091357-B2 Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2006-08-15 — — US disclosed
US-20030225142-A1 Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2003-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225142-A1 Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies CHRNA4, CHRNA2, CHRNA5 PTPN7 955/4885HMGCR 3107/4885RECQL 4046/4885
US-10570074-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-20180072645-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-11168046-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-20200385325-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885
US-20220098133-A1 1,3-Fatty Diol Compounds And Derivatives Thereof DGAT1, DGAT2, DSG1 PTPN7 4485/4885HMGCR 842/4885RECQL 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.