Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993899 | 0.91 | L3MBTL1 (0.48) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1991515 | 0.85 | RECQL (0.55) | L3MBTL1RECQLALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL15882015 | 0.84 | ROCK1 (0.53) | L3MBTL1ROCK1NAMPTF2PLAU | |
| SCHEMBL1991434 | 0.84 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1991437 | 0.84 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1994342 | 0.81 | RECQL (0.55) | L3MBTL1RECQLALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL1991871 | 0.80 | L3MBTL1 (0.48) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL17324782 | 0.80 | ROCK1 (0.55) | ROCK1NAMPTCHRM2CHRM4CHRM1 | |
| SCHEMBL15882047 | 0.80 | ROCK1 (0.55) | ROCK1NAMPTCHRM2CHRM4CHRM1 | |
| SCHEMBL23915623 | 0.80 | RECQL (0.47) | RECQLROCK1ALDH1A1SMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885RECQL 3604/4885ROCK1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.