SCHEMBL19949686

SCHEMBL19949686

[c]1cccc2c1C1(c3[c]cccc3-c3ccccc31)c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PDK2 Q15119 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
S100A4 P26447 1/20 0.32
ITGA4 P13612 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21858109 0.96 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL796811 0.88 MEN1 (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21858597 0.84 ALDH1A1 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22344977 0.84 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL16632998 0.82 MEN1 (0.66) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL16652935 0.82 MEN1 (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL16585087 0.79 PDK2 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL148320 0.79 PGR (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL20530157 0.79 MAPT (0.40) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL20530166 0.79 MAPT (0.44) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10930856-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-02-23 US disclosed
US-20200176686-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-06-04 US disclosed
US-10559760-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-11 US disclosed
WO-2018051207-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-22 WO disclosed
US-20180076394-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200176686-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SUN2, LEF1, TRPA1 KDM4E 1174/4885MEN1 1151/4885LMNA 606/4885
US-10559760-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SUN2, LEF1, TRPA1 KDM4E 1174/4885MEN1 1151/4885LMNA 606/4885
US-10930856-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SUN2, LEF1, TRPA1 KDM4E 1174/4885MEN1 1151/4885LMNA 606/4885
US-20180076394-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SUN2, LEF1, TRPA1 KDM4E 1174/4885MEN1 1151/4885LMNA 606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.