Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240516 | 0.86 | CYP3A4 (0.66) | CYP3A4NFKB1PMP22TYMSNR1H3 | |
| Hydrochloric Acid SCHEMBL29690161 | 0.85 | CYP3A4 (0.64) | CYP3A4NFKB1PMP22TYMSNR1H3 | |
| SCHEMBL6005895 | 0.82 | ESR1 (0.62) | TYMSNR1H3ESR1ESR2SCN2A | |
| SCHEMBL18917454 | 0.82 | CYP3A4 (0.65) | CYP3A4NFKB1PMP22NR1H3SCN2A | |
| SCHEMBL12733162 | 0.81 | ESR1 (0.51) | CYP3A4NFKB1PMP22TYMSNR1H3 | |
| SCHEMBL18806460 | 0.79 | CYP3A4 (0.61) | CYP3A4NFKB1PMP22NR1H3SCN2A | |
| SCHEMBL30268221 | 0.78 | TYMS (0.72) | TYMSNR1H3ESR1ESR2SCN2A | |
| SCHEMBL2150841 | 0.77 | MEN1 (0.55) | NR1H3ESR1ESR2SCN2ANR1H2 | |
| SCHEMBL8995310 | 0.77 | CYP3A4 (0.62) | CYP3A4NFKB1PMP22NR1H3ESR1 | |
| SCHEMBL5924351 | 0.76 | CYP3A4 (0.66) | CYP3A4NFKB1PMP22NR1H3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981905-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20180072655-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072655-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | ALDH7A1, ODC1, ASS1 | CYP3A4 627/4885NFKB1 1120/4885PMP22 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.