SCHEMBL199519

SCHEMBL199519

CCCC(C)(C)Sc1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.48
ESR2 Q92731 9/20 0.48
NR1H2 P55055 1/20 0.39
SLC6A2 P23975 4/20 0.37
SLC6A4 P31645 4/20 0.37
SLC6A3 Q01959 4/20 0.37
CYP3A4 P08684 4/20 0.37
LMNA P02545 3/20 0.37
HSD17B10 Q99714 3/20 0.37
AR P10275 2/20 0.37
TSHR P16473 2/20 0.37
HTR6 P50406 2/20 0.37
ESRRG P62508 2/20 0.37
TYR P14679 1/20 0.37
HPGD P15428 1/20 0.37
SHBG P04278 2/20 0.35
ADRA2A P08913 3/20 0.34
ADORA3 P0DMS8 3/20 0.34
TACR2 P21452 3/20 0.34
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL199752 0.89 ESR1 (0.52) ESR1ESR2NR1H2SLC6A2SLC6A4
SCHEMBL202011 0.83 ESR1 (0.45) ESR1ESR2NR1H2SLC6A2SLC6A4
SCHEMBL25984327 0.82 TSHR (0.34) SLC6A4TSHRHPGDALDH1A1ACHE
SCHEMBL199518 0.80 SLC6A4 (0.31) SLC6A4
SCHEMBL19387700 0.80 MAOA (0.36) SLC6A4CYP3A4HSD17B10TSHRHPGD
SCHEMBL1454164 0.79 ALDH1A1 (0.36) SLC6A2CYP3A4LMNAHSD17B10TSHR
SCHEMBL199652 0.78 SHBG (0.50) ESR1ESR2NR1H2SLC6A2SLC6A4
SCHEMBL3823413 0.77 ESR1 (0.42) ESR1ESR2NR1H2SLC6A2CYP3A4
SCHEMBL19066589 0.74 ESR1 (0.37) ESR1ESR2LMNAHSD17B10AR
SCHEMBL2480563 0.73 NR1H2 (0.50) ESR1ESR2NR1H2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
EP-2029573-B1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2011-10-26 EP disclosed
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF AKTIENGESELLSCHAFT (DE) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS TDO2, C9, CYP3A43 ESR1 2527/4885ESR2 1167/4885NR1H2 1954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.