Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601680 | 0.95 | MEN1 (0.41) | CHRNB2CHRNA6CHRNA4RAB9ANPC1 | |
| SCHEMBL20247449 | 0.79 | CHRNB2 (0.42) | CHRNB2CHRNA6CHRNA4RAB9ANPC1 | |
| SCHEMBL4807186 | 0.79 | HTR1B (0.47) | CHRNB2CHRNA6CHRNA4RAB9ANPC1 | |
| SCHEMBL12893078 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA6CHRNA4RAB9ANPC1 | |
| SCHEMBL3433200 | 0.77 | KDM4E (0.55) | CHRNB2CHRNA6CHRNA4RAB9AMEN1 | |
| SCHEMBL23028310 | 0.76 | MEN1 (0.45) | CHRNB2CHRNA6CHRNA4MEN1KMT2A | |
| SCHEMBL2601667 | 0.75 | CHRNB2 (0.42) | CHRNB2CHRNA4RAB9ANPC1MEN1 | |
| SCHEMBL920725 | 0.73 | ABCG2 (0.33) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12880403 | 0.72 | MCHR1 (0.47) | CHRNB2CHRNA6CHRNA4MEN1KMT2A | |
| SCHEMBL3764508 | 0.72 | HTR1B (0.35) | SMN1; SMN2KDM4EABCG2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048856-A1 | METHOD FOR EFFICIENT RADIOLABELING OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-15 | — | — | WO | disclosed |