Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126961 | 0.81 | CYP1A2 (0.50) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL3645477 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL2601680 | 0.80 | MEN1 (0.41) | CHRNB2CHRNA4MAPTKDM4EMAOA | |
| SCHEMBL27684835 | 0.79 | PDE5A (0.50) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL7245296 | 0.79 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL17672492 | 0.79 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL14224809 | 0.79 | CYP2C19 (0.56) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL28282489 | 0.78 | PDE5A (0.49) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL6655861 | 0.77 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL26797009 | 0.75 | PPIA (0.46) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680260-B2 | 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same | RIKEN (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20120101266-A1 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | RIKEN (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101266-A1 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | UMPS, APOBEC3G, FPR1 | CHRNB2 1434/4885CHRNA4 2154/4885CHRNB1 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.