Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.60 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL19953228 | 0.81 | LOXL2 (0.82) | LOXL2PRMT5WDR77MMP2MMP13 | |
| SCHEMBL19964478 | 0.75 | LOXL2 (1.00) | LOXL2PRMT5WDR77IDO1CDK5 | |
| SCHEMBL19953230 | 0.75 | LOXL2 (0.63) | LOXL2MMP2MMP13MMP14CYP1A2 | |
| SCHEMBL30880110 | 0.69 | LOXL2 (0.61) | LOXL2 | |
| SCHEMBL27195629 | 0.69 | LOXL2 (0.61) | LOXL2 | |
| SCHEMBL30880109 | 0.69 | LOXL2 (0.57) | LOXL2 | |
| SCHEMBL27195628 | 0.69 | LOXL2 (0.57) | LOXL2 | |
| SCHEMBL19953274 | 0.69 | LOXL2 (0.65) | LOXL2MMP2MMP13MMP14IDO1 | |
| Trifluoroacetic Acid SCHEMBL6066580 | 0.68 | DAO (0.46) | LOXL2CYP2C9 | |
| SCHEMBL19953414 | 0.67 | LOXL2 (0.57) | LOXL2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |