Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953634 | 0.84 | AADAT (0.37) | GRM7CHRM1MAPTMEN1KMT2A | |
| SCHEMBL19953533 | 0.82 | FABP5 (0.43) | FABP5GRM7MAPTMEN1KMT2A | |
| SCHEMBL19953489 | 0.82 | FABP5 (0.43) | FABP5GRM7MAPTMEN1KMT2A | |
| SCHEMBL19953584 | 0.82 | FABP5 (0.43) | FABP5GRM7MAPTMEN1KMT2A | |
| SCHEMBL19953537 | 0.82 | GRM7 (0.39) | FABP5GRM7CHRM1MAPTMEN1 | |
| SCHEMBL19953484 | 0.81 | GRM7 (0.43) | FABP5GRM7MAPTMEN1KMT2A | |
| SCHEMBL19953671 | 0.79 | ALDH1A1 (0.39) | MAPTMEN1KMT2AAADATALDH1A1 | |
| SCHEMBL19960700 | 0.79 | GRM7 (0.43) | FABP5GRM7MEN1KMT2ATRPV1 | |
| SCHEMBL19953656 | 0.77 | FABP5 (0.41) | FABP5GRM7MAPTHRH3MTNR1A | |
| SCHEMBL19960927 | 0.72 | KCNQ2 (0.44) | FABP5GRM7HRH3TRPV1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |