Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953499 | 0.77 | FABP5 (0.39) | FABP5HRH3MTNR1AMTNR1BEPHX2 | |
| SCHEMBL19953489 | 0.74 | FABP5 (0.43) | FABP5HRH3MTNR1AMTNR1BEPHX2 | |
| SCHEMBL19953584 | 0.74 | FABP5 (0.43) | FABP5HRH3MTNR1AMTNR1BEPHX2 | |
| SCHEMBL19953533 | 0.74 | FABP5 (0.43) | FABP5HRH3MTNR1AMTNR1BEPHX2 | |
| SCHEMBL19953514 | 0.72 | OPRM1 (0.43) | FABP5HRH3KCNQ2MTNR1AMTNR1B | |
| SCHEMBL19960560 | 0.71 | HRH3 (0.45) | FABP5HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL7132234 | 0.71 | CA12 (0.40) | MAPTKDM4E | |
| SCHEMBL19953667 | 0.70 | ACE (0.47) | FABP5HRH3MTNR1AMTNR1BGRM7 | |
| SCHEMBL19960927 | 0.69 | KCNQ2 (0.44) | FABP5HRH3KCNQ2MTNR1AMTNR1B | |
| SCHEMBL19953484 | 0.69 | GRM7 (0.43) | FABP5EPHX2MAPTGRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | claimed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |