Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12853726 | 0.89 | OPRD1 (0.38) | OPRD1OPRM1OPRK1OPRL1CYP1A2 | |
| SCHEMBL19339149 | 0.84 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1CYP1A2 | |
| SCHEMBL19954030 | 0.81 | DRD2 (0.47) | OPRM1 | |
| SCHEMBL4556736 | 0.81 | PDE4D (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL383177 | 0.77 | ESR2 (0.51) | — | |
| SCHEMBL10028305 | 0.77 | OPRL1 (0.46) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL383808 | 0.76 | CCR1 (0.41) | OPRD1OPRM1OPRK1OPRL1CYP1A2 | |
| SCHEMBL383232 | 0.76 | OPRD1 (0.40) | OPRD1OPRM1OPRK1OPRL1CYP1A2 | |
| SCHEMBL12853767 | 0.75 | DRD2 (0.47) | OPRM1 | |
| Hydrochloric Acid SCHEMBL384006 | 0.75 | OPRD1 (0.39) | OPRD1OPRM1OPRK1OPRL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914719-B2 | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 | ASTEX THERAPEUTICS LTD. (GB) | 2018-03-13 | — | — | US | disclosed |