Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560184 | 0.85 | TGFBR1 (0.38) | LRRK2TGFBR1 | |
| SCHEMBL19954631 | 0.85 | TGFBR1 (0.43) | LRRK2TGFBR1CNR2 | |
| SCHEMBL19954636 | 0.83 | NR3C2 (0.39) | LRRK2TGFBR1 | |
| SCHEMBL18164093 | 0.81 | LRRK2 (0.38) | CYP1A2LRRK2MAP3K12 | |
| SCHEMBL19953972 | 0.79 | CNR2 (0.32) | CNR2 | |
| SCHEMBL19954574 | 0.78 | MAP3K12 (0.43) | CYP1A2LRRK2TGFBR1MAP3K12 | |
| SCHEMBL24813965 | 0.77 | CNR2 (0.37) | MAP3K12CNR2 | |
| SCHEMBL19954641 | 0.76 | NR3C1 (0.35) | TGFBR1 | |
| SCHEMBL26012663 | 0.74 | CNR2 (0.35) | TGFBR1MAP3K12CNR2 | |
| SCHEMBL24815019 | 0.73 | NTRK1 (0.37) | TGFBR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |