Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866110 | 1.00 | MMP3 (0.32) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19955110 | 1.00 | MMP3 (0.32) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL20664927 | 1.00 | MMP3 (0.32) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19955112 | 1.00 | MMP3 (0.32) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL20664934 | 1.00 | MMP3 (0.32) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19955022 | 0.97 | MMP2 (0.33) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19955025 | 0.97 | MMP2 (0.33) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL18123722 | 0.82 | MMP9 (0.38) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19866117 | 0.81 | MMP2 (0.33) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL19866065 | 0.76 | MMP2 (0.31) | MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147624-A1 | CYCLOSPORIN ANALOG AND USE THEREOF | 睿诺医疗科技（上海）有限公司 | 2020-07-23 | — | — | WO | disclosed |
| US-9914755-B2 | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized | ALLERGAN, INC. (US) | 2018-03-13 | — | — | US | disclosed |