SCHEMBL1995686

SCHEMBL1995686

CCCCC(=O)Oc1cc(C(F)(F)F)ccc1C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.49
ALDH1A1 P00352 2/20 0.46
CYP2C19 P33261 2/20 0.46
USP2 O75604 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CES2 O00748 2/20 0.43
ALOX15 P16050 1/20 0.42
TLR2 O60603 2/20 0.42
TLR1 Q15399 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1991905 0.92 CYP2C19 (0.48) KDM4EKMT2AMEN1RECQLALDH1A1
SCHEMBL1996213 0.85 ALDH1A1 (0.50) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL21708733 0.85 KDM4E (0.45) KDM4EKMT2AMEN1RECQLALDH1A1
SCHEMBL15763984 0.82 CES2 (0.50) KDM4EKMT2AMEN1ALDH1A1CYP2C19
SCHEMBL1998648 0.81 MEN1 (0.60) KDM4EKMT2AMEN1RECQLALDH1A1
SCHEMBL1999397 0.78 KIF11 (0.49) KDM4EKMT2AMEN1RECQLALDH1A1
SCHEMBL15453673 0.78 KDM4E (0.51) KDM4EKMT2AALDH1A1CYP2C19USP2
SCHEMBL21708622 0.78 KMT2A (0.49) KDM4EKMT2AMEN1RECQLHPGD
SCHEMBL1994152 0.77 KDM4E (0.71) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL15453988 0.77 CES2 (0.55) KDM4EKMT2AMEN1ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed