Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 12/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505223 | 0.84 | VCAM1 (0.51) | VCAM1TDP1TSHRMAPK1NPBWR1 | |
| SCHEMBL2080018 | 0.82 | VCAM1 (0.50) | VCAM1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL23507272 | 0.79 | TSHR (0.49) | VCAM1TDP1MAPTALDH1A1MEN1 | |
| SCHEMBL19145140 | 0.79 | ALDH1A1 (0.55) | VCAM1TDP1MAPTALDH1A1MEN1 | |
| SCHEMBL9808913 | 0.78 | VCAM1 (0.51) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9808946 | 0.77 | VCAM1 (0.45) | VCAM1TDP1MAPTALDH1A1MEN1 | |
| SCHEMBL9808949 | 0.77 | VCAM1 (0.45) | VCAM1TDP1MAPTALDH1A1MEN1 | |
| SCHEMBL27703189 | 0.75 | ALDH1A1 (0.50) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10505466 | 0.74 | HSD17B10 (0.45) | VCAM1TDP1MAPTALDH1A1MEN1 | |
| SCHEMBL9808910 | 0.74 | MAPT (0.48) | VCAM1TDP1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3954687-A1 | PROCESSES AND INTERMEDIATES USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2022-02-16 | — | — | EP | disclosed |
| EP-3569588-A1 | PROCESS FOR PREPARING A SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2970263-B1 | PROCESSES FOR THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | ABBVIE INC (US) | 2018-05-09 | — | — | EP | disclosed |
| EP-3293185-A1 | PROCESSES FOR THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Inc. (US) | 2018-03-14 | — | — | EP | disclosed |