Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830795 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL19182644 | 0.83 | PDK1 (0.52) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL9808919 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL9808915 | 0.78 | PDGFRB (0.53) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL29453576 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL2211964 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL22137287 | 0.75 | SIRT6 (0.54) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL15486437 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL19145140 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TDP1HTTLMNAGAA | |
| SCHEMBL19956882 | 0.75 | VCAM1 (0.53) | ALDH1A1TDP1MAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492428-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | ACADEMIA SINICA | 2016-04-13 | — | — | CN | disclosed |
| CN-102256966-B | Solubility mTOR mixture and its conditioning agent | WHITEHEAD BIOMEDICAL INST (US) | 2016-02-10 | — | — | CN | disclosed |
| CN-102459202-B | As the inhibitor isoxazoline of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-105073768-A | Ras inhibitors and uses thereof | DANA FARBER CANCER INST INC | 2015-11-18 | — | — | CN | disclosed |
| CN-104910025-A | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY | 2015-09-16 | — | — | CN | disclosed |
| CN-104822837-A | Process for large scale enzymatic synthesis of oligosaccharides | ACADEMIA SINICA | 2015-08-05 | — | — | CN | disclosed |
| CN-104710487-A | Triterpene saponins, methods of synthesis, and uses thereof | SLOAN KETTERING INST CANCER | 2015-06-17 | — | — | CN | disclosed |
| CN-104718202-A | Processes for the preparation of (S)-3-4-((4-(morpholinomethyl) benzyl)oxy)-1-oxoisoindolin-2-yl) piperidine-2,6-dione and pharmaceutically acceptable forms thereof | CELGENE CORP | 2015-06-17 | — | — | CN | disclosed |
| CN-102781909-B | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104718193-A | Compositions, methods, and systems for synthesis and use of contrast agents | LANTHEUS MEDICAL IMAGING INC | 2015-06-17 | — | — | CN | disclosed |
| CN-101730708-B | Stitched polypeptides | HARVARD COLLEGE | 2013-09-18 | — | — | CN | disclosed |
| CN-103038240-A | Synthetic method for preparing ecteinascidin compounds | PHARMA MAR SA | 2013-04-10 | — | — | CN | disclosed |
| CN-102459202-A | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS INC | 2012-05-16 | — | — | CN | disclosed |
| CN-102256966-A | Soluble mtor complexes and modulators thereof | WHITEHEAD BIOMEDICAL INST | 2011-11-23 | — | — | CN | disclosed |
| CN-102245559-A | Aminoalcohol lipidoids and uses thereof | MASSACHUSETTS INST TECHNOLOGY | 2011-11-16 | — | — | CN | disclosed |
| CN-102177152-A | Halofuginone analogs for inhibition of tRNA synthetases and uses thereof | HARVARD COLLEGE | 2011-09-07 | — | — | CN | disclosed |
| CN-102112484-A | Triterpenoid saponin, and synthesis method and application thereof | SLOAN KETTERING INST CANCER | 2011-06-29 | — | — | CN | disclosed |
| CN-101932592-A | Antineoplastic compound | PHARMA MAR SA | 2010-12-29 | — | — | CN | disclosed |
| CN-101730708-A | stitched polypeptides | HARVARD COLLEGE | 2010-06-09 | — | — | CN | disclosed |
| CN-101189229-A | Synthesis of avrainvillamide, stephacidin B, and analogues thereof | HARVARD COLLEGE (US) | 2008-05-28 | — | — | CN | disclosed |