Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363422 | 0.81 | TPSAB1 (0.41) | SMN1; SMN2TSHRRECQLMEN1KMT2A | |
| SCHEMBL12114914 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAPOLBTSHRRECQL | |
| SCHEMBL1317530 | 0.75 | POLB (0.44) | SMN1; SMN2LMNAPOLBTSHRRECQL | |
| SCHEMBL30772071 | 0.75 | SLC6A1 (0.37) | SMN1; SMN2LMNATSHRKMT2AALDH1A1 | |
| SCHEMBL29370228 | 0.74 | TPSAB1 (0.41) | SMN1; SMN2TSHRRECQLKMT2AL3MBTL1 | |
| SCHEMBL19959156 | 0.71 | CHRNB2 (0.40) | SMN1; SMN2LMNATSHRKMT2ACHRM2 | |
| SCHEMBL28124706 | 0.71 | CHRM2 (0.35) | SMN1; SMN2LMNAPOLBTSHRKMT2A | |
| SCHEMBL28583310 | 0.69 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAPOLBTSHRRECQL | |
| SCHEMBL2146330 | 0.69 | KMT2A (0.42) | KMT2ATPSAB1TPSD1TPSG1P2RY12 | |
| SCHEMBL12520131 | 0.68 | TPSAB1 (0.45) | SMN1; SMN2LMNATSHRKMT2ATPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919856-B2 | Cyclohexene compounds and use thereof | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2021-02-16 | — | — | US | disclosed |
| US-20190241520-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2019-08-08 | — | — | US | disclosed |
| WO-2018045950-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241520-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | CYP51A1, FURIN, CYP21A2 | SMN1; SMN2 3334/4885LMNA 1000/4885POLB 3811/4885 |
| US-10919856-B2 | Cyclohexene compounds and use thereof | CYP51A1, FURIN, CYP21A2 | SMN1; SMN2 3334/4885LMNA 1000/4885POLB 3811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.