SCHEMBL19959776

SCHEMBL19959776

O=P(c1cccnc1)(c1ccc2ccccc2c1)c1cccc2c1nc1c3ccccc3c3ccccc3n21

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2C9 P11712 2/20 0.34
CYP11B1 P15538 2/20 0.32
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B2 P19099 1/20 0.32
USP2 O75604 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
POLB P06746 1/20 0.30
LMNA P02545 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
TOP1 P11387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19959815 0.91 POLB (0.33) ALDH1A1USP2POLBLMNATOP1
SCHEMBL19959824 0.90 TOP1 (0.35) POLBTOP1
SCHEMBL19959775 0.90 TOP1 (0.37) ALDH1A1USP2POLBLMNATOP1
SCHEMBL19959779 0.88 MEN1 (0.33) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL19959791 0.87 CYP2C9 (0.37) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL19959878 0.87 EGFR (0.32)
SCHEMBL19959870 0.86 ALDH1A1 (0.33) ALDH1A1CYP2C9POLBLMNATOP1
SCHEMBL19959910 0.85 USP2 (0.34) SMN1; SMN2NPC1RAB9AALDH1A1USP2
SCHEMBL19959790 0.85 SMN1; SMN2 (0.37) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL19959784 0.84 CYP2C9 (0.37) SMN1; SMN2MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-06-30 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 SMN1; SMN2 3857/4885MEN1 885/4885NPC1 3974/4885
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 SMN1; SMN2 3857/4885MEN1 885/4885NPC1 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.