Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953761 | 0.88 | ACHE (0.43) | ALDH1A1GHSRL3MBTL1HDAC4HDAC7 | |
| SCHEMBL19953760 | 0.88 | ACHE (0.43) | ALDH1A1GHSRL3MBTL1HDAC4HDAC7 | |
| SCHEMBL19953759 | 0.88 | ACHE (0.43) | ALDH1A1GHSRL3MBTL1HDAC4HDAC7 | |
| SCHEMBL19960586 | 0.81 | TRPV1 (0.32) | GHSRHDAC4HDAC7HDAC5MAPT | |
| SCHEMBL19960938 | 0.79 | ADRA2A (0.34) | ALDH1A1HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL19960839 | 0.78 | HDAC4 (0.39) | L3MBTL1HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL19960969 | 0.78 | DRD2 (0.33) | GHSRL3MBTL1HDAC4HDAC7HDAC5 | |
| Hydrochloric Acid SCHEMBL19953504 | 0.77 | HDAC4 (0.38) | L3MBTL1HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL19953489 | 0.74 | FABP5 (0.43) | L3MBTL1HDAC4HDAC7HDAC5MAPT | |
| SCHEMBL19953584 | 0.74 | FABP5 (0.43) | L3MBTL1HDAC4HDAC7HDAC5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |