Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 17/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953576 | 0.88 | ACE (0.41) | XIAP | |
| SCHEMBL19953575 | 0.88 | ACE (0.41) | XIAP | |
| SCHEMBL19953578 | 0.88 | ACE (0.41) | XIAP | |
| SCHEMBL19960686 | 0.85 | F11 (0.48) | XIAP | |
| SCHEMBL19960670 | 0.83 | GHSR (0.49) | GHSRDRD2 | |
| SCHEMBL19960718 | 0.82 | ACE (0.46) | GHSRXIAP | |
| SCHEMBL25142645 | 0.81 | GHSR (0.47) | GHSR | |
| SCHEMBL19960692 | 0.80 | ACE (0.44) | GHSR | |
| SCHEMBL12585837 | 0.79 | GHSR (0.45) | GHSRDRD2 | |
| SCHEMBL605316 | 0.78 | ACE (0.56) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |