Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075502 | 1.00 | CA12 (0.32) | CA12CA1CA2CA7CA14 | |
| SCHEMBL15424092 | 0.89 | ALDH1A1 (0.42) | CA2ALDH1A1TSHR | |
| SCHEMBL3925816 | 0.88 | — | — | |
| SCHEMBL18249518 | 0.88 | — | — | |
| SCHEMBL13159634 | 0.82 | TSHR (0.36) | TSHR | |
| SCHEMBL215109 | 0.82 | CA12 (0.39) | CA12CA1CA2CA7CA14 | |
| SCHEMBL1976929 | 0.81 | ALDH1A1 (0.46) | CA2ALDH1A1TSHR | |
| SCHEMBL4710785 | 0.81 | ALDH1A1 (0.35) | CA12CA1CA2CA7CA14 | |
| SCHEMBL18107268 | 0.79 | LMNA (0.50) | ALDH1A1TSHR | |
| SCHEMBL1995540 | 0.79 | LMNA (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418820-A | Carboxylic acid derivative as lysophosphatidic acid receptor antagonist | KBP BIOSCIENCES CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-8709280-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2014-04-29 | — | — | US | disclosed |
| US-8696933-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | VANDERBILT UNIVERSITY | 2012-10-04 | — | — | US | disclosed |
| US-20120205582-A1 | POLAR NEMATIC COMPOUNDS | VANDERBILT UNIVERSITY | 2012-08-16 | — | — | US | disclosed |
| US-8168084-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110147655-A1 | POLAR NEMATIC COMPOUNDS | NATIONAL SCIENCE FOUNDATION | 2011-06-23 | — | — | US | disclosed |
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205582-A1 | POLAR NEMATIC COMPOUNDS | BCOR, LATS1, LATS2 | CA12 1902/4885CA1 1405/4885CA2 1440/4885 |
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | LATS2, CCNH, CRY1 | CA12 2868/4885CA1 2522/4885CA2 2747/4885 |
| US-20110147655-A1 | POLAR NEMATIC COMPOUNDS | BCOR, LATS1, LATS2 | CA12 1902/4885CA1 1405/4885CA2 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.