SCHEMBL23723240

SCHEMBL23723240

C#CCn1c(=O)n(CC#C)c2cc(N)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.60
▸ KDM4E B2RXH2 2/20 0.60
▸ MAPT P10636 2/20 0.60
▸ GAA P10253 1/20 0.60
▸ GFER P55789 1/20 0.60
▸ PARG Q86W56 5/20 0.40
▸ CYP1A2 P05177 2/20 0.37
▸ ADORA3 P0DMS8 2/20 0.36
▸ CYP19A1 P11511 1/20 0.35
▸ BRPF1 P55201 2/20 0.34
▸ ADORA2B P29275 2/20 0.33
▸ ADORA2A P29274 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ HBB P68871 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17434292 0.79 KDM4E (0.52) ALDH1A1KDM4EMAPTGAAGFER
SCHEMBL13233782 0.77 ALDH1A1 (0.96) ALDH1A1KDM4EMAPTGAAGFER
SCHEMBL17434204 0.76 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTGAAGFER
Hydrochloric Acid SCHEMBL16736633 0.75 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTGAAGFER
SCHEMBL10504839 0.74 IDO1 (0.42) ALDH1A1MEN1HPGDMAPK1KMT2A
SCHEMBL19962798 0.72 MEN1 (0.40) ALDH1A1KDM4EMAPTGAAGFER
SCHEMBL1629499 0.70 ADORA2B (0.39) ADORA3ADORA2BADORA2A
SCHEMBL20569856 0.68 KDM4E (0.58) ALDH1A1KDM4EMAPTGAAGFER
SCHEMBL9380302 0.67 CYP1A2 (0.70) ALDH1A1GAAPARGCYP1A2ADORA3
SCHEMBL23723363 0.66 ALDH1A1 (0.68) ALDH1A1KDM4EMAPTGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 — — US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 — — US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO ALDH1A1 367/4885KDM4E 807/4885MAPT 3849/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 ALDH1A1 482/4885KDM4E 433/4885MAPT 3816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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