Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153405 | 0.81 | POLB (0.42) | KDM4EALDH1A1NPSR1MEN1HPGD | |
| SCHEMBL23130696 | 0.70 | TERT (0.35) | ALDH1A1LMNAMEN1HPGDKMT2A | |
| SCHEMBL23153403 | 0.70 | TERT (0.38) | — | |
| SCHEMBL23153396 | 0.67 | KAT2B (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL19962832 | 0.65 | TDP1 (0.42) | KDM4ELMNAALOX15 | |
| SCHEMBL19962167 | 0.65 | TDP1 (0.42) | KDM4ELMNAALOX15 | |
| SCHEMBL19962831 | 0.64 | POLB (0.36) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24810932 | 0.62 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14367687 | 0.61 | TERT (0.48) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5798620 | 0.61 | NQO2 (0.64) | KDM4ENQO2ALDH1A1LMNAPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| WO-2018048879-A1 | METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | TBCA, SLC39A3, TBL3 | KDM4E 2013/4885PARP14 2461/4885NQO2 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.