Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964310 | 0.91 | LOXL2 (0.53) | FLT3GRK2FAAHMGLLSLC2A1 | |
| SCHEMBL19964496 | 0.87 | IDO1 (0.48) | FLT3GRK2FAAHMGLLSLC2A1 | |
| SCHEMBL19964536 | 0.86 | FLT3 (0.42) | FLT3GRK2FAAHMGLLSLC2A1 | |
| SCHEMBL19953258 | 0.83 | IDO1 (0.46) | FLT3GRK2FAAHMGLLSLC2A1 | |
| SCHEMBL19421692 | 0.74 | FLT3 (0.51) | FLT3GRK2SLC2A1IDO1CYP11B1 | |
| SCHEMBL19953244 | 0.73 | LOXL2 (0.46) | ALDH1A1LOXL2 | |
| SCHEMBL4508334 | 0.71 | HDAC1 (0.52) | SLC2A1ALDH1A1IDO1CYP11B1CYP11B2 | |
| SCHEMBL2885662 | 0.70 | CYP11B1 (0.67) | ALDH1A1IDO1CYP11B1CYP11B2HDAC1 | |
| SCHEMBL4509302 | 0.69 | IDO1 (0.58) | GRK2ALDH1A1IDO1HDAC1HDAC6 | |
| SCHEMBL1867752 | 0.68 | CYP11B1 (0.55) | FLT3ALDH1A1NR1I2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |