Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | KCNN3 | Q9UGI6 | 14/20 | 0.51 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.51 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964763 | 0.80 | LOXL2 (0.74) | LOXL2 | |
| SCHEMBL19964787 | 0.78 | SMN1; SMN2 (0.48) | PDE10AKCNN3KCNN1KCNN2LOXL2 | |
| SCHEMBL7835023 | 0.74 | LOXL2 (0.49) | PDE10AKCNN3KCNN1KCNN2LOXL2 | |
| SCHEMBL7835390 | 0.73 | LOXL2 (0.51) | PDE10AKCNN3KCNN1KCNN2LOXL2 | |
| SCHEMBL7833635 | 0.73 | LOXL2 (0.48) | PDE10AKCNN3KCNN1KCNN2LOXL2 | |
| SCHEMBL11467425 | 0.73 | PDE10A (0.59) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL7831627 | 0.72 | LOXL2 (0.50) | PDE10AKCNN3KCNN1KCNN2LOXL2 | |
| SCHEMBL29869 | 0.71 | PDE10A (1.00) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL30974 | 0.68 | PDE10A (0.67) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL1290450 | 0.68 | PDE10A (0.67) | PDE10AKCNN3KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |