Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 5/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 5/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156593 | 0.85 | EZH2 (0.38) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21157287 | 0.84 | TSHR (0.41) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19964426 | 0.82 | NPC1 (0.41) | ALDH1A1 | |
| SCHEMBL21156563 | 0.81 | ALDH1A1 (0.35) | EZH2L3MBTL1EEDRBBP4SUZ12 | |
| SCHEMBL21113204 | 0.78 | RAB9A (0.42) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL21157293 | 0.78 | ALDH1A1 (0.39) | EZH2L3MBTL1EEDRBBP4SUZ12 | |
| SCHEMBL21157283 | 0.77 | ALOX15 (0.41) | ALDH1A1TSHR | |
| SCHEMBL21113144 | 0.76 | RAB9A (0.42) | L3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL21156531 | 0.76 | ALDH1A1 (0.40) | EZH2OPRK1EEDRBBP4SUZ12 | |
| SCHEMBL21157291 | 0.76 | EED (0.43) | EZH2L3MBTL1OPRK1EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |