Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964712 | 0.67 | RPS6KB1 (0.34) | — | |
| SCHEMBL21342369 | 0.65 | — | — | |
| SCHEMBL31590222 | 0.64 | GFER (0.44) | GFERGRM2KDM4EMEN1KMT2A | |
| Alcohol SCHEMBL28051180 | 0.64 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL17498784 | 0.64 | ABL1 (0.55) | KMT2AMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL1480961 | 0.63 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21157339 | 0.63 | BRD4 (0.48) | GFERGRM2KDM4EMAPTALDH1A1 | |
| Alcohol SCHEMBL29012469 | 0.63 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL14463968 | 0.62 | — | — | |
| SCHEMBL13224763 | 0.62 | RELA (0.44) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |