Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 4/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980792 | 0.80 | OXTR (0.44) | OXTRNNMTKDM1AHSD17B1HSD17B2 | |
| SCHEMBL5182975 | 0.77 | OXTR (0.44) | OXTRNNMTKDM1AAVPR1A | |
| SCHEMBL11803312 | 0.76 | OXTR (0.58) | OXTRNNMTAVPR1AALDH1A1MKNK1 | |
| SCHEMBL1238891 | 0.75 | OXTR (0.41) | OXTRNNMTAVPR1A | |
| SCHEMBL20789939 | 0.75 | GABRP (0.40) | OXTRALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL15926165 | 0.74 | OXTR (0.41) | OXTRAVPR1A | |
| SCHEMBL7672381 | 0.74 | OXTR (0.49) | OXTRNNMTHSD17B1HSD17B2AVPR1A | |
| SCHEMBL1238726 | 0.74 | OXTR (0.40) | OXTR | |
| SCHEMBL31563753 | 0.73 | ALDH1A1 (0.46) | ALDH1A1ALOX15TSHRHSD17B10KCNH2 | |
| SCHEMBL2100924 | 0.73 | ALDH1A1 (0.46) | ALDH1A1ALOX15TSHRHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399933-B2 | Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180072660-A1 | INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE FOR THE TREATMENT OF CANCER | BRISTOL MYERS SQUIBB CO (US) | 2018-03-15 | — | — | US | disclosed |
| CN-1070047-C | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 2001-08-29 | — | — | CN | disclosed |
| CN-1105234-A | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 1995-07-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072660-A1 | INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE FOR THE TREATMENT OF CANCER | IDO1, IDO2, INMT | OXTR 4139/4885NNMT 18/4885KDM1A 100/4885 |
| US-10399933-B2 | Inhibitors of indoleamine-2,3-dioxygenase for the treatment of cancer | IDO1, IDO2, INMT | OXTR 4139/4885NNMT 18/4885KDM1A 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.