Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364246 | 0.83 | MAPT (0.50) | CYP1A2KIF11GAAMAPTGFER | |
| SCHEMBL20270054 | 0.81 | KDM4E (0.62) | CASRNR1H4CYP1A2PPARGPPARA | |
| SCHEMBL6918008 | 0.81 | POLB (0.66) | CYP1A2KIF11GAAMAPTPEPD | |
| SCHEMBL10580566 | 0.80 | KMT2A (0.55) | KIF11GAAMAPTGFERPEPD | |
| SCHEMBL13544383 | 0.80 | MAPT (0.58) | MAPTPEPDPOLBAKR1C3ALDH1A1 | |
| SCHEMBL26544451 | 0.79 | NR1H4 (0.50) | CASRNR1H4CYP1A2PPARGPPARA | |
| SCHEMBL6853336 | 0.78 | NR1H4 (0.77) | NR1H4CYP1A2PPARGPPARAMAPT | |
| SCHEMBL1954485 | 0.78 | KIF11 (0.52) | KIF11GAAMAPTGFERPEPD | |
| SCHEMBL3047568 | 0.78 | ALDH1A1 (0.60) | CYP1A2KIF11GAAMAPTGFER | |
| SCHEMBL6827233 | 0.78 | KIF11 (0.52) | KIF11GAAMAPTGFERPEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045969-A1 | COMPOUND FOR ACTIVATING ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE | 法玛科技顾问股份有限公司 | 2018-03-15 | — | — | WO | disclosed |