SCHEMBL19968640

SCHEMBL19968640

IP(c1ccco1)c1ccco1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
POLB P06746 4/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 2/20 0.33
PKM P14618 2/20 0.33
PTPN7 P35236 2/20 0.33
BLM P54132 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 2/20 0.33
PTPN1 P18031 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406414 0.78
SCHEMBL41028 0.77 TP53 (0.41) TP53POLBKMT2AALDH1A1PKM
SCHEMBL3896544 0.74 TP53 (0.39) TP53POLBKMT2AALDH1A1PKM
SCHEMBL7600624 0.74 TP53 (0.39) TP53POLBKMT2AALDH1A1PKM
SCHEMBL4102518 0.74 TP53 (0.39) TP53POLBKMT2AALDH1A1PKM
SCHEMBL2214228 0.74 TP53 (0.39) TP53POLBKMT2AALDH1A1PKM
SCHEMBL1784193 0.74 TP53 (0.39) TP53POLBKMT2AALDH1A1PKM
SCHEMBL10343288 0.72 TP53 (0.38) TP53POLBKMT2AALDH1A1PKM
SCHEMBL21248108 0.72 TP53 (0.38) TP53POLBKMT2AALDH1A1PKM
SCHEMBL6756634 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-09 US disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-29 US disclosed
US-10702861-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-07 US disclosed
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US disclosed
US-10376869-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-13 US disclosed
US-10357764-B2 Phosphacycle compound and process for production thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-23 US disclosed
US-10207262-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-19 US disclosed
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-07 US disclosed
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM TP53 3073/4885POLB 1516/4885KMT2A 2522/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-10376869-B2 Process for oligomerization OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-10357764-B2 Phosphacycle compound and process for production thereof OXER1, PPIP5K2, IP6K1 TP53 4055/4885POLB 780/4885KMT2A 2447/4885
US-10207262-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM TP53 3073/4885POLB 1516/4885KMT2A 2522/4885
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885
US-10702861-B2 Process for oligomerization OXER1, NOD1, LIG1 TP53 3154/4885POLB 886/4885KMT2A 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.