Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998238 | 0.88 | MLNR (0.42) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL1995582 | 0.88 | MLNR (0.57) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL2003107 | 0.87 | MLNR (0.47) | KDM4EMLNR | |
| SCHEMBL2003279 | 0.87 | PRKAA2 (0.46) | KDM4EMLNRMEN1KMT2AALDH1A1 | |
| SCHEMBL1995199 | 0.86 | MLNR (0.58) | KDM4EMLNRMEN1KMT2AALDH1A1 | |
| SCHEMBL1998344 | 0.86 | MLNR (0.44) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL1999380 | 0.86 | MEN1 (0.48) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL2000794 | 0.84 | MLNR (0.45) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL1999298 | 0.83 | PRKAA2 (0.43) | KDM4EMLNRMEN1KMT2AMAPK1 | |
| SCHEMBL2002044 | 0.83 | MLNR (0.42) | KDM4EMLNRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964597-B2 | Piperazinyl-sulfonamide derivatives useful in the treatment of GPR38 receptor mediated diseases | GLAXO GROUP LIMITED (GB) | 2011-06-21 | — | — | US | disclosed |