Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | BCR | P11274 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998238 | 0.91 | MLNR (0.42) | MLNRKDM4E | |
| SCHEMBL2003110 | 0.88 | MLNR (0.63) | MLNRRETKDRMKNK2ABL1 | |
| SCHEMBL1996929 | 0.87 | KDM4E (0.46) | MLNRKDM4E | |
| SCHEMBL2849665 | 0.81 | MLNR (0.55) | MLNRRETKDRKDM4EABL1 | |
| SCHEMBL1999248 | 0.79 | MLNR (0.60) | MLNRRETKDRKDM4E | |
| SCHEMBL2003105 | 0.77 | MLNR (0.52) | MLNRKDM4E | |
| SCHEMBL2003279 | 0.77 | PRKAA2 (0.46) | MLNRKDM4E | |
| SCHEMBL1999431 | 0.76 | ALDH1A1 (0.34) | KDM4E | |
| SCHEMBL1998344 | 0.76 | MLNR (0.44) | MLNRKDM4E | |
| SCHEMBL1995199 | 0.76 | MLNR (0.58) | MLNRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964597-B2 | Piperazinyl-sulfonamide derivatives useful in the treatment of GPR38 receptor mediated diseases | GLAXO GROUP LIMITED (GB) | 2011-06-21 | — | — | US | disclosed |