Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 7/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19969987 | 0.81 | HTR3A (0.39) | L3MBTL1KDM4ENPC1BRD4MITF | |
| SCHEMBL19422008 | 0.70 | L3MBTL1 (0.46) | L3MBTL1KDM4ENPC1BRD4MITF | |
| SCHEMBL17176468 | 0.69 | HTR3A (0.58) | HTR3A | |
| SCHEMBL19969988 | 0.68 | SLC16A3 (0.40) | L3MBTL1KDM4ENPC1BRD4MITF | |
| SCHEMBL17170637 | 0.68 | HTR3A (0.56) | L3MBTL1HTR3A | |
| SCHEMBL12329417 | 0.67 | L3MBTL1 (0.45) | L3MBTL1MAPT | |
| SCHEMBL19068190 | 0.63 | L3MBTL1 (0.51) | L3MBTL1KDM4ENPC1BRD4MITF | |
| SCHEMBL25759525 | 0.62 | L3MBTL1 (0.40) | L3MBTL1KDM4ENPC1PDE5ARAB9A | |
| SCHEMBL19465595 | 0.61 | L3MBTL1 (0.42) | L3MBTL1KDM4ENPC1HTR3ACCR1 | |
| SCHEMBL31725552 | 0.61 | HTR3A (0.46) | HTR3AMAPTTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | TAKEDA CALIFORNIA, INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | HTR3A, HTR3B, HTR5A | L3MBTL1 3876/4885KDM4E 3871/4885NPC1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.