Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998156 | 0.79 | MET (0.46) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL1833612 | 0.72 | POLB (0.42) | CSNK2A1CDK1CDK4CCNB1CCNA2 | |
| SCHEMBL1993559 | 0.69 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1996585 | 0.69 | MAPK14 (0.60) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL1994949 | 0.67 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11CDK1 | |
| SCHEMBL2000094 | 0.67 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL6640716 | 0.67 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11CDK1 | |
| SCHEMBL1994561 | 0.64 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11CDK1 | |
| SCHEMBL13379720 | 0.63 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11CDK1 | |
| SCHEMBL17840562 | 0.63 | TGFBR1 (0.63) | MAPK14TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |