Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999001 | 0.81 | MAPK14 (0.69) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1997010 | 0.79 | MAPK14 (0.42) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2286613 | 0.70 | MET (0.67) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2785987 | 0.69 | MAPK14 (0.73) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL13379720 | 0.68 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11CCNB2 | |
| SCHEMBL1996761 | 0.68 | MAPK14 (0.51) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2125635 | 0.67 | IDO1 (0.47) | MAPK14MAPK13MAPK12MAPK11NUDT1 | |
| SCHEMBL2886849 | 0.66 | MAPK14 (0.70) | METMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL26910396 | 0.65 | TGFBR1 (0.40) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL2786751 | 0.65 | CCNB2 (0.49) | MAPK14MAPK13MAPK12MAPK11CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |