Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL5827367 | 0.88 | TDP1 (0.59) | LMNATDP1MEN1KMT2ASNCA | |
| Amiloxate SCHEMBL19899316 | 0.82 | LMNA (0.71) | LMNATDP1PTGER4PTGER3PTGER2 | |
| Amiloxate SCHEMBL1768923 | 0.81 | LMNA (0.90) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL8095776 | 0.77 | LMNA (1.00) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL2228053 | 0.77 | LMNA (1.00) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL2228049 | 0.77 | LMNA (1.00) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL15765 | 0.77 | LMNA (1.00) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL15764 | 0.77 | LMNA (1.00) | LMNATDP1THRBATMMEN1 | |
| Amiloxate SCHEMBL31304727 | 0.76 | LMNA (0.97) | LMNATDP1THRBATMMEN1 | |
| SCHEMBL39304 | 0.75 | ALDH1A1 (0.48) | LMNAMEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442354-A1 | COMPOSITION AND PRODUCTION OF SPINACH EXTRACT WITH SS-ECDYSONE | Symrise AG (DE) | 2019-02-20 | — | — | EP | disclosed |
| EP-3416612-A1 | FRAGRANT MIXTURES CONTAINING ESTERS AND KETONES | Symrise AG (DE) | 2018-12-26 | — | — | EP | disclosed |
| EP-3294262-A1 | LIQUID COOLANT PREPARATIONS | Symrise AG (DE) | 2018-03-21 | — | — | EP | disclosed |