Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342293 | 1.00 | RIPK1 (0.48) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL2421671 | 0.90 | GRIA4 (0.40) | RIPK1TAAR1 | |
| SCHEMBL18575544 | 0.87 | HDAC4 (0.38) | RIPK1TAAR1CACNA1FCHRM2CHRM1 | |
| SCHEMBL5664123 | 0.77 | RIPK1 (0.63) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL20427677 | 0.74 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL21322418 | 0.74 | TAAR1 (0.56) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL28133086 | 0.74 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL2418232 | 0.74 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL21471659 | 0.73 | RIPK1 (0.48) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL585429 | 0.73 | TRPA1 (0.48) | RIPK1TAAR1AOC3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| EP-3344678-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | Sika Technology AG (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |