Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342293 | 0.90 | RIPK1 (0.48) | RIPK1TAAR1 | |
| SCHEMBL19971104 | 0.90 | RIPK1 (0.48) | RIPK1TAAR1 | |
| SCHEMBL18575544 | 0.84 | HDAC4 (0.38) | GRIA4TSHRTP53TYRRIPK1 | |
| SCHEMBL5918492 | 0.74 | RIPK1 (0.46) | GRIA4RIPK1ACHEESR1ESR2 | |
| SCHEMBL731115 | 0.71 | — | — | |
| SCHEMBL23956932 | 0.70 | TAAR1 (0.39) | GRIA4RIPK1ACHEESR1ESR2 | |
| SCHEMBL166235 | 0.69 | GRIA4 (0.51) | GRIA4TSHRTP53TYRACHE | |
| SCHEMBL5413888 | 0.69 | TYR (0.45) | TSHRTP53TYRACHECYP2D6 | |
| SCHEMBL10831182 | 0.67 | GRIA4 (0.38) | GRIA4TSHRTP53STAT3ACHE | |
| SCHEMBL5803512 | 0.67 | GRIA4 (0.49) | GRIA4TSHRTP53RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-10392480-B2 | Catalyst containing amidine groups | SIKA TECHNOLOGY AG (CH) | 2019-08-27 | — | — | US | disclosed |
| EP-3344678-B1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECH AG (CH) | 2019-07-03 | — | — | EP | disclosed |
| EP-3180382-B1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECH AG (CH) | 2018-10-10 | — | — | EP | disclosed |
| US-20180171082-A1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-06-21 | — | — | US | disclosed |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-05-31 | — | — | US | disclosed |
| EP-3138864-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | Sika Technology AG (CH) | 2017-03-08 | — | — | EP | disclosed |
| US-8430989-B2 | Hydroxyaldimine-containing polyurethane composition | SIKA TECHNOLOGY AG (CH) | 2013-04-30 | — | — | US | disclosed |
| US-20110214810-A1 | HYDROXYALDIMINE-CONTAINING POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2011-09-08 | — | — | US | disclosed |
| EP-2194081-B1 | Polyurethane composition comprising hydroxyaldimines | SIKA TECHNOLOGY AG (CH) | 2011-09-07 | — | — | EP | disclosed |
| EP-2194081-A1 | Polyurethane composition comprising hydroxyaldimines | Sika Technology AG (CH) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110214810-A1 | HYDROXYALDIMINE-CONTAINING POLYURETHANE COMPOSITION | ADH1A, ODC1, ADH1C | GRIA4 1304/4885TSHR 4792/4885TP53 4560/4885 |
| US-10414875-B2 | Catalyst containing guanidine groups | GMPS, GMNN, RNMT | GRIA4 923/4885TSHR 4857/4885TP53 3797/4885 |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | GMPS, RNMT, GMNN | GRIA4 1380/4885TSHR 4847/4885TP53 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.