Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068049 | 0.88 | HTR6 (0.35) | HTR6IDEFGFR4SMN1; SMN2FBP1 | |
| SCHEMBL16626801 | 0.87 | HTR6 (0.36) | HTR6IDEFGFR4SMN1; SMN2HTR2A | |
| Hydrochloric Acid SCHEMBL16619116 | 0.86 | HTR6 (0.35) | HTR6IDEFGFR4SMN1; SMN2HTR2A | |
| SCHEMBL19971350 | 0.85 | IDE (0.35) | HTR6IDE | |
| SCHEMBL16618986 | 0.85 | HDAC1 (0.34) | HTR6IDEFGFR4SMN1; SMN2 | |
| SCHEMBL16626800 | 0.83 | HDAC1 (0.33) | HTR6IDEHTR2A | |
| SCHEMBL19971354 | 0.82 | HTR6 (0.38) | HTR6IDESMN1; SMN2HTR2A | |
| SCHEMBL19971348 | 0.75 | HTR6 (0.36) | HTR6IDEHTR2A | |
| SCHEMBL16626788 | 0.73 | HTR6 (0.39) | HTR6IDEFGFR4HTR2A | |
| SCHEMBL17971552 | 0.73 | HTR6 (0.41) | HTR6IDEFGFR4FBP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |