Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626797 | 0.87 | HTR6 (0.39) | HTR6PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL16619085 | 0.86 | HTR6 (0.38) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16619373 | 0.84 | PDE4A (0.36) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626798 | 0.82 | TTK (0.39) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626668 | 0.81 | HTR6 (0.40) | HTR6DRD2IDERORC | |
| SCHEMBL19971353 | 0.81 | HTR6 (0.41) | HTR6DRD2IDERORCHTR2A | |
| SCHEMBL19971533 | 0.81 | HTR6 (0.39) | HTR6PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL16618810 | 0.81 | HTR6 (0.41) | HTR6DRD2IDERORCHTR2A | |
| SCHEMBL19971401 | 0.79 | HTR6 (0.39) | HTR6IDEPPARGPPARDPPARA | |
| SCHEMBL19971361 | 0.78 | HTR6 (0.36) | HTR6DRD2IDEPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |