Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618911 | 0.84 | HTR6 (0.42) | HTR6IDESMN1; SMN2DRD2HTR2A | |
| SCHEMBL19971353 | 0.83 | HTR6 (0.41) | HTR6IDEDRD2PTGDRPTGDR2 | |
| SCHEMBL19971351 | 0.82 | HTR6 (0.33) | HTR6IDESMN1; SMN2HTR2A | |
| SCHEMBL16618767 | 0.80 | HTR6 (0.39) | HTR6IDESMN1; SMN2DRD2PTGDR | |
| SCHEMBL19971366 | 0.78 | HTR6 (0.41) | HTR6IDEDRD2PTGDRPTGDR2 | |
| SCHEMBL16626799 | 0.77 | HTR6 (0.36) | HTR6IDEDRD2HTR2AHTR2C | |
| SCHEMBL16618590 | 0.73 | HTR6 (0.38) | HTR6SMN1; SMN2DRD2HTR2AALDH1A1 | |
| SCHEMBL19971533 | 0.73 | HTR6 (0.39) | HTR6IDEPTGDRPTGDR2HTR2A | |
| SCHEMBL19971401 | 0.73 | HTR6 (0.39) | HTR6IDEPTGDRPTGDR2PPARG | |
| SCHEMBL19971426 | 0.71 | RORC (0.45) | HTR6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |