Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | HTR6 | P50406 | 6/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626667 | 0.89 | RORC (0.37) | RORCHTR6ADORA2AADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL16619121 | 0.88 | RORC (0.37) | RORCHTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL16619178 | 0.87 | RORC (0.40) | RORCHTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL19971369 | 0.85 | RORC (0.39) | RORCHTR6PPARG | |
| SCHEMBL16626662 | 0.84 | RORC (0.37) | RORCHTR6ADORA2AADORA2BADORA1 | |
| SCHEMBL16626655 | 0.74 | RORC (0.39) | RORCHTR6L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL16619006 | 0.74 | RORC (0.40) | RORCHTR6L3MBTL1ALDH1A1HDAC6 | |
| SCHEMBL16618638 | 0.73 | HTR6 (0.42) | RORCHTR6L3MBTL1ALDH1A1HDAC6 | |
| Hydrochloric Acid SCHEMBL16618977 | 0.73 | RORC (0.39) | RORCHTR6L3MBTL1KMT2A | |
| SCHEMBL16626748 | 0.73 | RORC (0.38) | RORCHTR6L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |