Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.39 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.37 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626748 | 0.88 | RORC (0.38) | RORCSLC20A2SLC20A1ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL16618931 | 0.88 | RORC (0.38) | RORCSLC20A2SLC20A1ALOX15MAPT | |
| SCHEMBL16618751 | 0.86 | SLC20A2 (0.43) | RORCSLC20A2SLC20A1ALOX15NPC1 | |
| SCHEMBL16618638 | 0.86 | HTR6 (0.42) | RORCSLC20A2SLC20A1ALOX15MAPT | |
| SCHEMBL16619006 | 0.86 | RORC (0.40) | RORCSLC20A2SLC20A1ALOX15NPC1 | |
| SCHEMBL16619379 | 0.85 | RORC (0.37) | RORCSLC20A2SLC20A1ALOX15MAPT | |
| SCHEMBL19971355 | 0.85 | RORC (0.38) | RORCPPARGHTR6 | |
| SCHEMBL16619007 | 0.84 | HTR6 (0.42) | NPC1HTR6 | |
| SCHEMBL16626659 | 0.84 | RORC (0.37) | RORCSLC20A2SLC20A1CYP3A4CYP2D6 | |
| SCHEMBL16619023 | 0.83 | HDAC1 (0.43) | RORCSLC20A2SLC20A1ALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |