Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 7/20 | 0.35 |
| ▸ | BCL2 | P10415 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971347 | 0.85 | POLB (0.37) | POLBHTR6BCL2MCL1IDE | |
| SCHEMBL16626641 | 0.84 | POLB (0.38) | POLBHTR6BCL2MCL1MAPT | |
| SCHEMBL16619019 | 0.84 | HTR6 (0.39) | POLBHTR6BCL2MCL1BCL2L1 | |
| SCHEMBL16619016 | 0.84 | HTR6 (0.39) | POLBHTR6BCL2MCL1BCL2L1 | |
| Hydrochloric Acid SCHEMBL16618961 | 0.84 | POLB (0.38) | POLBHTR6BCL2MCL1MAPT | |
| SCHEMBL16626642 | 0.81 | HTR6 (0.35) | POLBHTR6BCL2MCL1BCL2L1 | |
| SCHEMBL19971345 | 0.78 | IDE (0.43) | HTR6IDE | |
| SCHEMBL28207563 | 0.76 | IDE (0.42) | HTR6IDE | |
| SCHEMBL28857516 | 0.76 | IDE (0.41) | HTR6IDE | |
| SCHEMBL16626787 | 0.75 | HTR6 (0.40) | HTR6IDEMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |