Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626439 | 0.89 | LMNA (0.39) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| Hydrochloric Acid SCHEMBL16619117 | 0.88 | LMNA (0.38) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| SCHEMBL16619162 | 0.86 | LMNA (0.41) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| SCHEMBL16618640 | 0.83 | LMNA (0.41) | LMNAHTTSMN1; SMN2NAMPTABL1 | |
| SCHEMBL16626427 | 0.83 | HTR6 (0.40) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| Hydrochloric Acid SCHEMBL16618642 | 0.82 | HTR6 (0.40) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| SCHEMBL19971356 | 0.82 | IDE (0.37) | HTTSMN1; SMN2NAMPTKDRCHRNB4 | |
| SCHEMBL16626430 | 0.81 | LMNA (0.38) | LMNAHTTSMN1; SMN2NAMPTPPARG | |
| SCHEMBL17971524 | 0.81 | HTR6 (0.43) | SMN1; SMN2NAMPTCHRNB4CHRNA3TSHR | |
| Hydrochloric Acid SCHEMBL16618657 | 0.81 | LMNA (0.38) | LMNAHTTSMN1; SMN2NAMPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |