Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971358 | 0.91 | ALK (0.39) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL19971401 | 0.88 | HTR6 (0.39) | IDEFBP1ALKHDAC1HDAC6 | |
| SCHEMBL19971392 | 0.87 | POLB (0.38) | NAMPTPOLBHTTFBP1DHODH | |
| SCHEMBL16626413 | 0.86 | NAMPT (0.37) | IDEPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL16619306 | 0.86 | NAMPT (0.37) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16619211 | 0.85 | TNFSF11 (0.38) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626073 | 0.83 | HTR6 (0.39) | PDE4APDE4BPDE4CPDE4DNAMPT | |
| SCHEMBL16626410 | 0.82 | NAMPT (0.36) | IDEPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL17959702 | 0.82 | HTR6 (0.39) | PDE4APDE4BPDE4CPDE4DNAMPT | |
| SCHEMBL19971474 | 0.82 | LMNA (0.39) | NAMPTHTTKDRFBP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |