Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971352 | 0.87 | PDE4A (0.42) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16618846 | 0.86 | HTR6 (0.43) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16619093 | 0.83 | HTR6 (0.40) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626752 | 0.81 | HTR6 (0.37) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19971348 | 0.81 | HTR6 (0.36) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19971401 | 0.81 | HTR6 (0.39) | HTR6ALKIDERORCPTGDR | |
| SCHEMBL16619084 | 0.77 | HTR6 (0.46) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16619072 | 0.77 | RORC (0.41) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626620 | 0.76 | SLC6A2 (0.43) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16618894 | 0.76 | RORC (0.40) | HTR6PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |