Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971358 | 0.93 | ALK (0.39) | HTR6ALK | |
| SCHEMBL19971356 | 0.88 | IDE (0.37) | IDEALKHDAC1HDAC6FBP1 | |
| SCHEMBL19971361 | 0.87 | HTR6 (0.36) | HTR6IDEPPARGPPARDPPARA | |
| SCHEMBL16626508 | 0.86 | HTR6 (0.43) | HTR6IDEPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL16619225 | 0.85 | HTR6 (0.42) | HTR6IDEPPARGPPARDPPARA | |
| SCHEMBL16619159 | 0.84 | HDAC1 (0.41) | HTR6IDEPPARGPPARDPPARA | |
| SCHEMBL16626507 | 0.82 | HDAC1 (0.38) | HTR6IDERORCHDAC1HDAC2 | |
| SCHEMBL19971533 | 0.81 | HTR6 (0.39) | HTR6IDEPPARGRORCALK | |
| SCHEMBL16626514 | 0.81 | HTR6 (0.38) | HTR6PPARGPPARDPPARAALK | |
| Hydrochloric Acid SCHEMBL16618685 | 0.80 | HTR6 (0.37) | HTR6PPARGPPARDPPARAALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |