Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27360793 | 0.98 | ESR1 (0.54) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL577068 | 0.98 | ESR1 (0.57) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27874664 | 0.97 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27655928 | 0.97 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25299360 | 0.97 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL9525088 | 0.85 | SLC6A4 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL237613 | 0.82 | PTGS2 (0.56) | ESR1PTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL10442969 | 0.81 | PTGS2 (0.50) | ESR1PTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL312147 | 0.81 | KMT2A (0.76) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL11201814 | 0.81 | ALOX15 (0.58) | KMT2ASMN1; SMN2ALOX15PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068734-A | THERAPEUTIC AGENT | BOOTS CO PLC (GB) | 1993-02-10 | — | — | CN | claimed |
| US-20180078516-A1 | Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration | Innovazone Labs LLC | 2018-03-22 | — | — | US | disclosed |
| WO-2018053423-A1 | PHARMACEUTICAL COMPOSITION OF IBUPROFEN SODIUM FOR ORAL ADMINISTRATION | Innovazone Labs LLC (US) | 2018-03-22 | — | — | WO | disclosed |
| CN-1068305-C | Therapeutic agent | BOOTS CO PLC (GB) | 2001-07-11 | — | — | CN | disclosed |
| CN-1068734-A | THERAPEUTIC AGENT | BOOTS CO PLC (GB) | 1993-02-10 | — | — | CN | disclosed |